PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease

Metabolism. 150:155736. (2024)

Sachan V, Le Dévéhat M, Roubtsova A, Essalmani R, Laurendeau JF, Garçon D, Susan-Resiga D, Duval S, Mikaeeli S, Hamelin J, Evagelidis A, Chong M, Paré G, Chernetsova E, Gao ZH, Robillard I, Ruiz M, Trinh VQ, Estall JL, Faraj M, Austin RC, Sauvageau M, Prat A, Kiss RS, Seidah NG

Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration

Nature Communications. 13:7077. (2022)

Tran V, Nahlé S, Robert A, Desanlis I, Killoran R, Ehresmann S, Thibault MP, Barford D, Ravichandran KS, Sauvageau M, Smith MJ, Kmita M, Côté JF

The Tug1 locus is essential for male fertility

Genome Biology. 21:237. (2020)

Lewandowski JP, Dumbović G, Watson AR, Hwang T, Jacobs-Palmer E, Chang N, Much C, Turner KM, Kirby C, Rubinstein ND, Groff AF, Liapis SC, Gerhardinger C, Bester A, Pandolfi PP, Clohessy JG, †Hoekstra HE, †Sauvageau M, †Rinn JL.

Diverging RNPs: Toward Understanding lncRNA-Protein Interactions and Functions

Advances in Experimental Medicine & Biology. 1203:285-312. (2019)

Sauvageau M.

An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance

Cell. 173:649-664.e20. (2018)

Bester AC, Lee JD, Chavez A, Lee YR, Nachmani D, Vora S, Victor J, Sauvageau M, Monteleone E, Rinn JL, Provero P, Church GM, Clohessy JG, Pandolfi PP.

In vivo characterization of linc-p21 reveals functional cis-regulatory DNA elements

Cell Reports. 16:2178-2186. (2016)

Groff AF, Sanchez-Gomez DB, Soruco MML, Gerhardinger C, Barutcu AR, Li E, Elcavage L, Plana O, Sanchez LV, Lee JC, Sauvageau M, Rinn JL.

Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain

PNAS. 112:6855-6862. (2015)

*Goff LA, *Groff AF, *Sauvageau M, Trayes-Gibson Z, Sanchez-Gomez DB, Morse M, Martin RD, Elcavage LE, Liapis SC, Gonzalez-Celeiro M, Plana O, Li E, Gerhardinger C, Tomassy GS, Arlotta P, Rinn JL.

Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre

Nature Structural & Molecular Biology. 21:198-206. (2014)

Hacisuleyman E, Goff LA, Trapnell C, Williams A, Henao-Mejia J, Sun L, McClanahan P, Hendrickson DG, Sauvageau M, Kelley DR, Morse M, Engreitz J, Lander ES, Guttman M, Lodish HF, Flavell R, Raj A, Rinn JL.

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

eLife. 2:e01749. (2013)

Sauvageau M, Goff LA, Lodato S, Bonev B, Groff AF, Gerhardinger C, Sanchez-Gomez DB, Hacisuleyman E, Li E, Spence M, Liapis SC, Mallard W, Morse M, Swerdel MR, D'Ecclessis MF, Moore JC, Lai V, Gong G, Yancopoulos GD, Frendewey D, Kellis M, Hart RP, Valenzuela DM, Arlotta P, Rinn JL.

Long noncoding RNAs regulate adipogenesis

PNAS. 110:3387-3392. (2013)

Sun L, Goff LA, Trapnell C, Alexander R, Lo KA, Hacisuleyman E, Sauvageau M, Tazon-Vega B, Kelley DR, Hendrickson DG, Yuan B, Kellis M, Lodish HF, Rinn JL.

Differential analysis of gene regulation at transcript resolution with RNA-seq

Nature Biotechnology. 31:46-53. (2013)

Trapnell C, Hendrickson DG, Sauvageau M, Goff L, Rinn JL, Pachter L.

Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia

Blood. 120:e17-27. (2012)

*Trost M, *Sauvageau M, Hérault O, Deleris P, Pomiès C, Chagraoui J, Mayotte N, Meloche S, Sauvageau G, Thibault P.

A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia

Genes & Development. 26:651-656. (2012)

Simon C, Chagraoui J, Krosl J, Gendron P, Wilhelm B, Lemieux S, Boucher G, Chagnon P, Drouin S, Lambert R, Rondeau C, Bilodeau A, Lavallée S, Sauvageau M, Hébert J, Sauvageau G.

Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer

Cell Stem Cell. 7:299-313. (2011)

Sauvageau M,Sauvageau G.

Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia

Blood. 111:790-799. (2008)

Sauvageau M, Miller M, Lemieux S, Lessard J, Hébert J, Sauvageau G.